Neurological Disorders

The human body has an Endocannabinoid System (ECS), not a Benzodiazepine System. The receptors of the ECS system (namely CB1) play pivotal roles in anxiolytic action of benzodiazepines. In other words, benzodiazepine drugs (such as Alprazolam -“Xanax”; Chlordiazepoxide -“Librium”; Clobazepam – “Onfi”; Clonazepam -“Klonopin”; and many others) have an anxiolytic mechanism of action that utilize the ECS receptor CB1.   The ECS is emerging as primary drug targets for treating numerous neurological disorders including: Parkinson’s disease; Alzheimer’s disease; multiple sclerosis; neuropathic pain; schizophrenia; anxiety; depression; addiction; post-concussion syndrome, and post-traumatic stress disorders. Many peer reviewed research papers are using phytocannabinoids such as CBD to confirm the widely held assertion that natural plant medicine is as effective as pharmaceutical drugs for addressing nurological discorders.

What are the Scientists Saying about ECS and Neuro?


Cannabinoid and Endocannabinoid system’s role in neurological disorders

Authors: Cristino L , Bisogono T , Di Marzo  DOI: 10.1038/s41582-019-0284-z Here is what this research means for you : Anecdotal evidence is that cannabis preparations have medical benefits together with the discovery of the psychotropic plant-cannabinoid Δ -tetrahydrocannabinol (THC). It started efforts to develop THC-based therapeutics. Disappointment has marked these efforts, especially...

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What are the Scientists Saying about ECS and Epilepsy?

Cannabidiol (CBD) ‘s Effect on Epilepsy

Pharmacological and Therapeutic Properties of CBD for Epilepsy Authors : Franco V , Perucca   DOI : 10.1007 / s40265-019-01171-4S What is CBD ?  Cannabidiol ( CBD ) is a major active component of the Cannabis plant (Hemp ) , which, unlike tetrahydrocannabinol ( THC ), lacks excitement-inducing properties. During the last 10 years, there has been increasing interest in the use of CBD - enriched...

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What are the Scientists Saying about ECS and Dementia?

Cannabidiol (CBD) ‘s Effect on Dementia

Cannabinoids for the Neuropsychiatric Symptoms of Dementia ( NPS ) : A Systematic Review and Meta Analysis PMID : 31835954 DOI : 10.1177 / 0706743719892717 Here is what this research means for you :   Dementia patients have doubled over 26 years from the 1990s to 2016 while 90% of them showed symptoms of Neuropsychiatric Dementia ( NPS ). This led to researches for safer therapies,...

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What are the Scientists Saying about ECS and Parkinson’s Disease?

Cannabidiol (CBD) ‘s Effect on Parkinson’s disease

Therapeutic role of cannabinoid receptors and Effects on Parkinson's disease : What is Parkinson's Disease?  Parkinson's disease ( PD ) with common symptoms as tremors or spasms, is a neurodegenerative disease and its characteristic is the progressive degeneration of dopamine-producing neurons in ( SN ) of the midbrain. There is hardly any clinically proven efficient therapeutics for its cure in...

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What are the Scientists Saying about ECS and Cannabinoids?

The Interplay between the Endocannabinoid System , Epilepsy and Cannabinoids

Authors : Cheung KAK , Peiris H , Wallace G , Holland OJ , Mitchell MD PMID : 31810321 PMCID : PMC6929011 DOI : 10.3390/IJMS202376079 What is Epilepsy? Epilepsy is a neurological disorder that affects approximately 50 million people worldwide. Common symptoms of Epilepsy are Uncontrollable jerking and shaking called a "fit" Losing awareness and staring blankly into space. Becoming stiff &...

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What are the Scientists Saying about ECS and GABAergic Transmission?

GABAARs and Effect of Phytocannabinoids on GABAergic Transmission

GABAARs and Effect of Phytocannabinoids on GABAergic Transmission What is GABAARs GABAA Receptors ?  GABAARs (Gamma γ-Aminobutyric acid type A receptors ) are the receptors and mediatory inhibitors ( Ligand-gated ion channel) in the plasma membrane of neurons located in the limbic area of the brain, primarily responsible for Feelings and Emotions, they play mediating role during the nerve...

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